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Several thousand chemical compounds can occur in food, but only few
of them have nutritional significance. The human diet contains a huge variety
of non-nutrient components whose implications in health are virtually unknown.
In recent times, some evidences have been contributed that some dietary
non-nutrient phytochemicals (polyphenols, glucosinolates, phytoestrogens,
terpens, etc.) could be related to variations in the incidence of degenerative
or chronic diseases, such as cardiovascular diseases and some cancers These
compounds have only recently begun to be studied with respect to their
physiological properties or epidemiological significance. However, the
validity of the epidemiological studies is usually limited by the paucity
of the data available on food composition with regard to non-nutrient phytochemicals.
On the other hand, data on absorption and metabolism of these substances
in the human body are almost lacking. Even if they are not absorbed, they
will reach the colon where they interact with the gut microflora, giving
place to metabolites with might be absorbed or have some influence on gut
flora metabolism and gut flora composition (prebiotic effects)
 .
In this PSE meeting it is intended to revise the state-of-the-art about
health implications of natural non-nutrient phytochemicals. Important topics
to be treated will be structure–function relationships, bioavailability
and mechanisms of body uptake and transport, metabolism, effects of dietary
phytochemicals and their metabolites on gene expression and cell apoptosis
and proliferation, …. Major attention will be paid to data obtained from
human studies and the development of new methodologies to study diet and
health links including biomarkers of exposure and effect. Furthermore,
attention will be also devoted to the new coming aspects of genomics and
proteomics in phytochemical research. At the present moment several
projects related to phytochemicals have been funded within the Fifth Framework
Programme (FP-V), which are expected to offer their first results in the
following months. Because of the advances made by then this meeting is
ideally placed for all the researches working in this field building on
the new advances and obtaining preliminary conclusions. Conclusions obtained
should contribute to promote improved dietary advice on diet and health
based on scientific knowledge. Furthermore, information on optimal levels
of dietary phytochemicals could facilitate appropriate development of novel
and functional foods. The dates of the meeting also allow to think of it
as a good starting point for the definition of new research strategies
in this field and the launching of new proposals facing the coming FP-VI
| Celestino Santos-Buelga |
IUniversity of Salamanca, Spain (chairman) |
| David Lindsay |
IFR Norwich, UK |
| Mike Clifford |
University of Surrey, UK |
| Lars Dragsted |
Institute of Food Safety and Toxicology, Denmark |
| Herman Adlercreutz |
University of Helsinky, Finland |
| Angela Stafford |
Phytera Ltd, Honorary Chairman of PSE, UK |
| Eduardo Rosa |
University of Tras-os-Montes e Alto Douro, Portugal |
| Augustin Scalbert |
INRA Clermont-Ferrand, France |
| Begoña Olmedilla |
Hospital Puerta del Hierro, Madrid, Spain |
| Arnold Vlietinck |
University of Antwerpen, Belgium |
| José Luis Revuelta |
University of Salamanca, Spain |
| Francisco A. Tomás-Baberán |
CEBAS-CSIC Murcia, Spain |
| Julián Rivas-Gonzalo |
University of Salamanca, Spain |
| Celestino Santos-Buelga |
University of Salamanca, Spain |
| Julián Rivas Gonzalo (chairman) |
| Cristina García-Viguera |
| Francisco A. Tomás-Barberán |
| Celestino Santos-Buelga |
| Susana González Manzano (meeting secretary) |
| Carlos Cordón Marcos (meeting secretary) |
An important part of the scientific programme will be constituted by
invited lectures (12-15 presentations) where the most relevant aspects
in the three meeting topics are expected to be revised by acknowledged
experts. A time would also be allocated in the different sessions for presentation
of a few short oral communications, selected for their interest by the
scientific committee among those submitted by the participants. There will
be, of course, free contributions in poster format. All the invited lectures
will be published in a special issue of a scientific journal. The possibility
of publishing a book of Proceedings containing the full text of the rest
of communications (including posters) is also considered by the organisers.
A half a day session will be reserved for a satellite workshop on FP-V-granted
projects related to phytochemicals. With this aim coordinators of currently
active European projects will be invited to expose their results and preliminary
conclusions. Furthermore, Dr. Liam Breslin from Research Directorate-General
of European Commission has accepted to present the lines of the coming
FP-VI.
The official language of the Symposium is English (invited lectures,
abstracts and written papers).
The expected duration of the Symposium is 2.5 days and it will be mainly
focused to the following topics:
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Bioavailability of Phytochemicals
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Epidemiology and effects
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Biomakers of exposure and effect
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Genomics and proteomics in phytochemical research
Confirmed Lecturers
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"How does diet affect the development of age-related diseases?", Dr.
Barry Halliwell, University of Singapore (opening lecture).
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"DNA microarrays: a versatile approach for gene expression profiling. Applications
in phytochemical research". Dr. Arnaud Bovy, Plant Research International,
Wageningen, NL
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"Phytochemicals decrease oxidative DNA damage; but does this explain the
protective effects of fruits and vegetables against cancer?". Dr. Andrew
Collins, Rowett Research Institute, Aberdeen, UK
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"Metabolomic approaches for understanding nutritional effects". Dr.
Oliver Fiehn, Max-Planck-Institute of Molecular Plant Physiology, Potsdam,
Germany.
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"Health benefits of Folates". Dr. Paul Finglas, Institute of Food
Research, Norwich, UK.
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A comprehensive study on metabolism of isoflavones in human subjects".
Dr.
Satu-Maarit Heinonen, University of Helsinki, Finland.
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"Glucosinolates in the human diet: bioavailability and implications for
health". Dr. Ian Johnson, Institute of Food Research, Norwich, UK.
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"Use of microarrays on delineating the biological action of phytooestrogens".
Dr Tracy Murphy, Syngenta Central Toxicology Laboratory, Cheshire,
UK.
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"Bioinformatics and the new challenges of Genomics and Proteomics".
Dr. Alfonso Valencia, Centro de Nacional de Biotecnología, Madrid,
Spain.
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"Flavonoid pathway engineering". Dr. R. de Vos, Plant Research International,
Wageningen, NL.
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"Effect of metabolism of phytochemicals in vivo and in vitro on gene expression".Dr.
Gary Williamson, Institute of Food Research, Norwich, UK.
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Dr. C. Keen University of California, Davis.
The complete text of all the invited lectures will be published in ‘Phytochemistry
Reviews’. Contacts have also been established for the possible publication
of a special issue of the British Journal of Nutrition (Supplement Series)
containing full papers of those original free communications that the authors
may wish to submit to consideration of the journal.
Participants wishing to present a paper are invited to
submit an abstracts before January 15, 2002. The abstracts will
be evaluated by the Scientific Committee, and acceptance and the type of
presentation notified to contributors. All accepted abstracts will be printed
in the Abstracts Book to be distributed during the Conference.
The abstracts should be a one-page document in RTF or
Word 97 formats based on unpublished material and written in English.
They must content title, authors, addresses and phone, fax and e-mail of
the corresponding author and clearly specify whether the contribution is
expected to be an oral or poster presentation. Participants can send their
abstracts by e-mail as an attached document file to phytochem@usal.es
or by mailing a PC-compatible diskette to the Symposium Secretariat. The
following format is required:
Margins: Upper 3 cm, lower 2.5 cm, left 3 cm, right 2.5 cm
Title: Times New Roman 14, bold, centred.
Authors: Times New Roman 12, centred.
Example: Thomson, J.K.; Martin, L.H.; Silva, M.N.
Address: Times New Roman 12, centred.
Text: Times New Roman 12, fully justified.
Skip a line between the title
and authors and between the heading and the main text.
No include figures or
tables.
Indicate references with
a number.
References: Times New Roman 10
Example:
(1)
Arts, I.C.W., Hollman, P.C.H. and Kromhout, D. (1999). Chocolate as a source
of tea
flavonoids. Lancet 354, 488-489.
Before March 15, 2002:
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PSE members, students unemployed and retired people: 240 €
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Rest of participants: 350 €
After March 15, 2002:
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PSE members, students unemployed and retired people: 300 €
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Rest of participants: 410€
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accompanying people: 100 €
Fees for accompanying will include invitation to the gala dinner, a guided
visit to Salamanca and an excursion (lunch included) to the very typical
villages of the ‘Sierra de Salamanca’.
Four travel bursaries, each worth 150 pounds sterling, will be attributed
to students selected by the Organising Committee. Students wishing to apply
for one of these bursaries should send a short CV (one sheet) together
with the abstract of his/her presentation. The recipients of the travel
bursaries are expected to make an oral presentation at the meeting.
Exchange Rates
 
Colegio
Arzobispo Fonseca
A gala dinner will take place on the second day of the Symposium (50
€).
A country party will be also organised on Saturday 20th afternoon/evening
in case a sufficient number of people will be interested (about 50 €).
There will be a programme for accompanying people.
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 Accommodation
form
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Download and fill in the accomodation form and send it to "VIAJES
Y CONGRESOS" by post, fax or e-mail
The hotel reservation is apart from the registration. Booking is to
be made by contacting directly the travel agency. In order to do it, download
the accommodation form and send it to the agency by post, fax or e-mail.
Please, do it as soon as posible since problems for accommodation may exists,
as Salamanca is European City for Culture 2002 and lots of events are programmed |
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The closest airports to Salamanca are Valladolid (110 km)
or Madrid (200 km).The best choice is to fly to Madrid. From Madrid to
Salamanca you can either take a train or
a bus. The journey takes about 2.5h.
Trains
to Salamanca leave from Madrid-Chamartin
Station. The bus company is called “Auto-Res”
and its bus station in Madrid is located at “Plaza
Conde de Casal”. Fom the airport the train and bus stations can be
reached by underground
or taxi. The train station is on the line 10 of the Madrid
underground (get off at 'Chamartin'). The bus station is on line 6
(circle line), get off at 'Conde de Casal' and then walk for about 200
m.
The Valladolid airport has connections to many Spanish
airports. From Valladolid (15 km from the airport) you can take a regular
bus or train service to Salamanca.
Salamanca also has a small airport but only receives a
few domestic flights. Consult your travel agency.
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fax
post